:root {
  color-scheme: light;
  --navy: #09111f;
  --navy-2: #111d31;
  --navy-line: rgba(173, 196, 228, 0.18);
  --on-navy: #eef3fb;
  --on-navy-muted: #a9b8cc;
  --mint: #56e0c5;
  --mint-ink: #087967;
  --mint-deep: #065c4f;
  --mint-wash: #e8f7f3;
  --mint-line: #9fdccf;
  --blue: #6a8cff;
  --blue-ink: #3552c9;
  --blue-wash: #eef2ff;
  --bg: #f3f6fa;
  --paper: #ffffff;
  --soft: #f7f9fc;
  --text: #0d1a2b;
  --text-2: #2b3a4f;
  --muted: #536379;
  --line: #dfe5ee;
  --line-strong: #bcc7d6;
  --amber-ink: #82500d;
  --amber-wash: #fdf4e4;
  --amber-line: #e3b46c;
  --red-ink: #a62334;
  --red-line: #e2a7af;
  --focus: #1f5fd1;
  --wrap: 1160px;
  --gutter: 40px;
  --radius: 10px;
  --radius-sm: 6px;
  --shadow: 0 1px 2px rgba(9, 17, 31, 0.05), 0 8px 24px rgba(9, 17, 31, 0.06);
  --font: ui-sans-serif, -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif;
  --mono: ui-monospace, "SF Mono", SFMono-Regular, Menlo, Consolas, "Liberation Mono", monospace;
}

* { box-sizing: border-box; }
[hidden] { display: none !important; }
html {
  scroll-behavior: smooth;
  scroll-padding-top: 16px;
  -webkit-text-size-adjust: 100%;
  text-size-adjust: 100%;
}
body {
  margin: 0;
  min-width: 0;
  color: var(--text);
  background: var(--bg);
  font-family: var(--font);
  font-size: 1rem;
  line-height: 1.55;
}
img, svg { display: block; flex-shrink: 0; }
a { color: var(--blue-ink); text-underline-offset: 3px; text-decoration-thickness: 1px; }
a:hover { text-decoration-thickness: 2px; }
button, input, textarea { font: inherit; color: inherit; }
button { -webkit-tap-highlight-color: transparent; }
button, a, label, summary { touch-action: manipulation; }
h1, h2, h3, h4 { margin: 0; color: inherit; text-wrap: balance; }
p, ul, ol, dl, dd { margin: 0; }
ul, ol { padding: 0; }
.mono { font-family: var(--mono); font-size: 0.9em; letter-spacing: -0.01em; }

:focus-visible { outline: 3px solid var(--focus); outline-offset: 2px; }
.site-header :focus-visible,
.hero :focus-visible,
.site-footer :focus-visible { outline-color: var(--mint); }

.visually-hidden {
  position: absolute;
  width: 1px;
  max-width: 1px;
  height: 1px;
  padding: 0;
  margin: -1px;
  overflow: hidden;
  clip: rect(0 0 0 0);
  clip-path: inset(50%);
  white-space: nowrap;
  border: 0;
}
.skip-link {
  position: fixed;
  z-index: 40;
  left: 16px;
  top: 12px;
  transform: translateY(-160%);
  padding: 10px 14px;
  border-radius: var(--radius-sm);
  background: var(--mint);
  color: var(--navy);
  font-weight: 700;
  text-decoration: none;
}
.skip-link:focus { transform: translateY(0); }

.wrap { width: min(var(--wrap), calc(100% - var(--gutter))); margin-inline: auto; }

/* Shared type */
.panel-label, .kicker {
  display: block;
  color: var(--mint-ink);
  font: 600 0.68rem/1.3 var(--mono);
  letter-spacing: 0.1em;
  text-transform: uppercase;
}
.count, .tag {
  flex-shrink: 0;
  color: var(--muted);
  font: 500 0.78rem/1.3 var(--mono);
  white-space: nowrap;
}
.tag {
  padding: 3px 8px;
  border: 1px solid var(--line);
  border-radius: 999px;
}
.status-line { color: var(--muted); font-size: 0.84rem; }
.status-line:empty { display: none; }

/* Buttons */
.button {
  min-height: 42px;
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: 8px;
  padding: 9px 15px;
  border: 1px solid transparent;
  border-radius: var(--radius-sm);
  font-size: 0.92rem;
  font-weight: 650;
  line-height: 1.25;
  text-align: center;
  text-decoration: none;
  cursor: pointer;
  transition: background-color 140ms ease, border-color 140ms ease, color 140ms ease;
}
.button-primary { color: #fff; background: var(--navy); }
.button-primary:hover { background: var(--navy-2); }
.button-quiet { color: var(--text-2); background: var(--paper); border-color: var(--line-strong); }
.button-quiet:hover { border-color: var(--text-2); }
.button-danger { color: var(--red-ink); background: var(--paper); border-color: var(--red-line); }
.button-danger:hover { border-color: var(--red-ink); background: #fff5f6; }
.button:disabled { opacity: 0.45; cursor: not-allowed; }
.icon-button {
  width: 36px;
  height: 36px;
  display: inline-grid;
  place-items: center;
  padding: 0;
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  background: var(--paper);
  color: var(--text-2);
  cursor: pointer;
}
.icon-button:hover { border-color: var(--line-strong); color: var(--text); }

/* Header and hero */
.site-header { background: var(--navy); color: var(--on-navy); }
.header-inner {
  min-height: 56px;
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 16px;
}
.brand {
  display: inline-flex;
  align-items: center;
  gap: 10px;
  color: #fff;
  font-size: 1.02rem;
  font-weight: 700;
  letter-spacing: -0.01em;
  text-decoration: none;
}
.brand img { border-radius: 7px; }
.privacy-status {
  display: inline-flex;
  align-items: center;
  gap: 6px;
  padding: 4px 10px 4px 8px;
  border: 1px solid var(--navy-line);
  border-radius: 999px;
  color: var(--mint);
  font: 600 0.76rem/1.2 var(--mono);
  letter-spacing: 0.02em;
}

.hero {
  padding: 22px 0 76px;
  background:
    radial-gradient(60% 140% at 100% 0%, rgba(86, 224, 197, 0.1), transparent 60%),
    var(--navy);
  color: var(--on-navy);
}
.hero h1 {
  max-width: 22ch;
  font-size: clamp(1.6rem, 1.15rem + 1.9vw, 2.45rem);
  line-height: 1.12;
  letter-spacing: -0.025em;
  font-weight: 720;
  color: #fff;
}
.hero-boundary {
  margin-top: 10px;
  color: var(--on-navy-muted);
  font-size: 0.95rem;
}
.hero-boundary b { color: var(--mint); font-weight: 650; }

/* Workspace */
.workspace {
  position: relative;
  margin-top: -52px;
  display: grid;
  grid-template-columns: minmax(0, 1.55fr) minmax(300px, 1fr);
  gap: 20px;
  align-items: start;
}
.side { display: grid; gap: 20px; min-width: 0; }
.card {
  min-width: 0;
  padding: 22px;
  border: 1px solid var(--line);
  border-radius: var(--radius);
  background: var(--paper);
  box-shadow: var(--shadow);
}
.card-head {
  display: flex;
  align-items: baseline;
  justify-content: space-between;
  gap: 12px;
  margin-bottom: 14px;
}
.card-head h2 { font-size: 1.08rem; line-height: 1.3; letter-spacing: -0.01em; }
.card-sub { margin: -6px 0 14px; color: var(--muted); font-size: 0.88rem; }

/* Library */
.search-control {
  position: relative;
  display: flex;
  align-items: center;
}
.search-control svg {
  position: absolute;
  left: 13px;
  color: var(--muted);
  pointer-events: none;
}
.search-control input {
  width: 100%;
  min-height: 46px;
  padding: 10px 14px 10px 40px;
  border: 1px solid var(--line-strong);
  border-radius: var(--radius-sm);
  background: var(--soft);
  font-size: 1rem;
  transition: border-color 140ms ease, background-color 140ms ease;
}
.search-control input:hover { border-color: var(--muted); }
.search-control input:focus-visible { outline-offset: 0; background: var(--paper); border-color: var(--focus); }
.search-control input::placeholder { color: #7a889b; }

.medicine-grid {
  margin-top: 14px;
  display: grid;
  grid-template-columns: repeat(auto-fill, minmax(min(100%, 190px), 1fr));
  gap: 8px;
}
.medicine-grid:empty { display: none; }
.medicine-card {
  position: relative;
  min-width: 0;
  min-height: 64px;
  display: flex;
  flex-direction: column;
  justify-content: center;
  gap: 3px;
  padding: 11px 14px;
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  background: var(--paper);
  text-align: left;
  cursor: pointer;
  transition: border-color 140ms ease, background-color 140ms ease, box-shadow 140ms ease;
}
.medicine-card:hover { border-color: var(--line-strong); background: var(--soft); }
.medicine-card[aria-expanded="true"] {
  border-color: var(--navy);
  box-shadow: inset 3px 0 0 var(--mint-ink);
  background: var(--paper);
}
.medicine-name { font-size: 0.96rem; font-weight: 650; line-height: 1.3; }
.medicine-genes {
  color: var(--mint-ink);
  font: 500 0.76rem/1.35 var(--mono);
  overflow-wrap: anywhere;
}
.medicine-added {
  align-self: flex-start;
  margin-top: 2px;
  padding: 1px 6px;
  border-radius: 999px;
  background: var(--mint-wash);
  color: var(--mint-deep);
  font: 600 0.64rem/1.5 var(--mono);
  letter-spacing: 0.04em;
  text-transform: uppercase;
}
.library-empty {
  margin-top: 14px;
  padding: 14px 16px;
  border: 1px dashed var(--line-strong);
  border-radius: var(--radius-sm);
  font-size: 0.88rem;
}
.library-empty p { margin-top: 4px; color: var(--muted); }

/* Medicine detail */
.medicine-detail {
  margin-top: 16px;
  padding-top: 18px;
  border-top: 1px solid var(--line);
}
.detail-head {
  display: flex;
  align-items: flex-start;
  justify-content: space-between;
  gap: 12px;
}
.detail-head h3 { font-size: 1.3rem; line-height: 1.25; letter-spacing: -0.015em; }
.detail-head h3:focus { outline: none; }
.detail-head h3:focus-visible { outline: 3px solid var(--focus); outline-offset: 3px; }
.topic-genes { margin-top: 2px; color: var(--mint-ink); font: 500 0.82rem/1.4 var(--mono); }
.topic-question {
  margin-top: 14px;
  padding: 14px 16px;
  border-radius: var(--radius-sm);
  background: var(--mint-wash);
}
.topic-question-label {
  display: block;
  color: var(--mint-deep);
  font: 600 0.68rem/1.3 var(--mono);
  letter-spacing: 0.1em;
  text-transform: uppercase;
}
.topic-question p { margin-top: 4px; font-size: 0.98rem; font-weight: 550; line-height: 1.45; }
.topic-add-button {
  margin-top: 12px;
  min-height: 40px;
  padding: 8px 14px;
  border: 0;
  border-radius: var(--radius-sm);
  background: var(--navy);
  color: #fff;
  font-size: 0.9rem;
  font-weight: 650;
  cursor: pointer;
}
.topic-add-button:hover { background: var(--navy-2); }
.topic-add-button:disabled { background: transparent; color: var(--mint-deep); padding-inline: 0; cursor: default; }
.topic-sections {
  margin-top: 16px;
  display: grid;
  grid-template-columns: minmax(130px, 0.32fr) minmax(0, 1fr);
  gap: 10px 20px;
  font-size: 0.9rem;
}
.topic-sections dt { color: var(--muted); font-size: 0.8rem; font-weight: 650; line-height: 1.45; padding-top: 1px; }
.topic-sections dd { color: var(--text-2); }
.topic-sources {
  margin-top: 16px;
  padding-top: 12px;
  border-top: 1px solid var(--line);
  display: flex;
  flex-wrap: wrap;
  align-items: baseline;
  gap: 4px 8px;
  font-size: 0.86rem;
}
.topic-sources-label { color: var(--muted); font: 600 0.68rem/1.3 var(--mono); letter-spacing: 0.1em; text-transform: uppercase; }
.topic-reviewed { color: var(--muted); font-size: 0.8rem; }
.topic-update {
  flex-basis: 100%;
  margin-top: 6px;
  padding: 8px 10px;
  border-left: 3px solid var(--amber-line);
  background: var(--amber-wash);
  color: var(--amber-ink);
}
.topic-boundary { margin-top: 10px; color: var(--muted); font-size: 0.78rem; }

.topic-add-hint { margin-top: 6px; color: var(--amber-ink); font-size: 0.82rem; }
.library-write { margin-top: 10px; max-width: 100%; justify-content: flex-start; text-align: left; }
.library-write > span { min-width: 0; overflow-wrap: anywhere; }
.library-write-about { font-weight: 500; }
.library-full { color: var(--amber-ink); font-size: 0.8rem; }

/* Questions */
.question-list { list-style: none; display: grid; gap: 8px; }
.question-item {
  min-width: 0;
  display: grid;
  gap: 6px;
  padding: 10px 12px 6px;
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  background: var(--paper);
}
.question-item.is-editing { border-color: var(--navy); box-shadow: inset 3px 0 0 var(--mint-ink); }
.question-body { min-width: 0; }
.question-head { display: flex; flex-wrap: wrap; align-items: baseline; gap: 2px 8px; min-width: 0; }
.question-index { color: var(--mint-ink); font: 600 0.72rem/1 var(--mono); }
.question-name { min-width: 0; font-size: 0.9rem; line-height: 1.35; overflow-wrap: anywhere; }
.provenance {
  padding: 1px 6px;
  border-radius: 999px;
  background: var(--mint-wash);
  color: var(--mint-deep);
  font: 600 0.62rem/1.5 var(--mono);
  letter-spacing: 0.04em;
  text-transform: uppercase;
}
.provenance.is-custom { background: var(--amber-wash); color: var(--amber-ink); }
.question-text {
  margin-top: 3px;
  color: var(--text-2);
  font-size: 0.84rem;
  line-height: 1.45;
  white-space: pre-line;
  overflow-wrap: anywhere;
}
.question-notes { margin-top: 4px; font-size: 0.8rem; }
.question-notes > summary {
  width: fit-content;
  min-height: 28px;
  display: flex;
  align-items: center;
  color: var(--muted);
  font-weight: 600;
  cursor: pointer;
}
.question-notes p { color: var(--text-2); white-space: pre-line; overflow-wrap: anywhere; }
.question-controls { display: flex; flex-wrap: wrap; gap: 2px 4px; margin-left: -8px; }
.item-button {
  min-width: 44px;
  min-height: 36px;
  display: inline-flex;
  align-items: center;
  justify-content: center;
  padding: 4px 8px;
  border: 1px solid transparent;
  border-radius: var(--radius-sm);
  background: none;
  color: var(--text-2);
  font-size: 0.8rem;
  font-weight: 600;
  cursor: pointer;
}
.item-button:hover:not(:disabled) { border-color: var(--line-strong); background: var(--soft); }
.question-remove:hover:not(:disabled) { border-color: var(--red-line); color: var(--red-ink); }
.item-button:disabled { opacity: 0.4; cursor: not-allowed; }
.question-list .empty-state {
  padding: 12px;
  border: 1px dashed var(--line-strong);
  border-radius: var(--radius-sm);
  color: var(--muted);
  font-size: 0.88rem;
  text-align: center;
}
.write-button {
  width: 100%;
  min-height: 44px;
  margin-top: 8px;
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: 8px;
  padding: 9px 14px;
  border: 1px dashed var(--mint-ink);
  border-radius: var(--radius-sm);
  background: var(--paper);
  color: var(--mint-deep);
  font-size: 0.92rem;
  font-weight: 650;
  cursor: pointer;
  transition: background-color 140ms ease, border-color 140ms ease;
}
.write-button:hover:not(:disabled) { border-style: solid; background: var(--mint-wash); }
.write-button:disabled { border-color: var(--line-strong); background: var(--soft); color: var(--muted); cursor: not-allowed; }

.question-editor {
  margin-top: 10px;
  display: grid;
  gap: 12px;
  padding: 14px;
  border: 1px solid var(--line-strong);
  border-radius: var(--radius-sm);
  background: var(--soft);
}
.editor-head { display: flex; flex-wrap: wrap; align-items: baseline; justify-content: space-between; gap: 4px 10px; }
.editor-head h3 { min-width: 0; font-size: 1rem; line-height: 1.3; overflow-wrap: anywhere; }
.editor-context { color: var(--muted); font-size: 0.8rem; line-height: 1.45; }
.field { min-width: 0; display: grid; gap: 4px; }
.field-row { display: flex; align-items: center; justify-content: space-between; gap: 8px; }
.field label { color: var(--text); font-size: 0.86rem; font-weight: 650; }
.field-optional { color: var(--muted); font-weight: 500; }
.field input, .field textarea, .copy-fallback textarea {
  width: 100%;
  min-height: 44px;
  padding: 10px 12px;
  border: 1px solid var(--line-strong);
  border-radius: var(--radius-sm);
  background: var(--paper);
  font-size: 1rem;
  line-height: 1.45;
}
.field textarea { min-height: 96px; resize: vertical; }
.field input:focus-visible, .field textarea:focus-visible, .copy-fallback textarea:focus-visible { outline-offset: 0; border-color: var(--focus); }
.field [aria-invalid="true"] { border-color: var(--red-ink); box-shadow: inset 0 0 0 1px var(--red-ink); }
.field-help { display: flex; flex-wrap: wrap; justify-content: space-between; gap: 2px 8px; color: var(--muted); font-size: 0.76rem; }
.field-count { justify-self: end; margin-left: auto; color: var(--muted); font: 500 0.72rem/1.4 var(--mono); white-space: nowrap; }
.field-count.is-over { color: var(--red-ink); font-weight: 700; }
.text-button {
  justify-self: start;
  min-height: 36px;
  padding: 4px 0;
  border: 0;
  background: none;
  color: var(--blue-ink);
  font-size: 0.84rem;
  font-weight: 600;
  text-decoration: underline;
  text-underline-offset: 3px;
  cursor: pointer;
}
.entry-error {
  padding: 8px 10px;
  border-left: 3px solid var(--red-ink);
  border-radius: 0 var(--radius-sm) var(--radius-sm) 0;
  background: #fff5f6;
  color: var(--red-ink);
  font-size: 0.84rem;
  font-weight: 600;
}
.editor-actions { display: flex; flex-wrap: wrap; gap: 8px; }
.editor-actions .button { flex: 1 1 110px; min-height: 44px; }

.tray-note { margin-top: 10px; color: var(--muted); font-size: 0.8rem; line-height: 1.45; }
.tray-actions { margin-top: 12px; display: flex; flex-wrap: wrap; gap: 8px; }
.tray-actions .button { flex: 1 1 auto; }
.copy-fallback {
  margin-top: 12px;
  display: grid;
  gap: 8px;
  padding: 12px;
  border: 1px solid var(--amber-line);
  border-radius: var(--radius-sm);
  background: var(--amber-wash);
}
.copy-fallback label { color: var(--amber-ink); font-size: 0.84rem; font-weight: 650; }
.copy-fallback textarea { min-height: 180px; resize: vertical; white-space: pre-wrap; }
.copy-fallback .button { justify-self: start; }
#question-status { margin-top: 10px; }
#question-status[data-tone="error"] { color: var(--red-ink); font-weight: 600; }

/* DNA intake */
.consent-row {
  display: grid;
  grid-template-columns: auto minmax(0, 1fr);
  gap: 10px;
  padding: 12px;
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  background: var(--soft);
  cursor: pointer;
}
.consent-row:hover { border-color: var(--line-strong); }
.consent-row:has(input:checked) { border-color: var(--mint-line); background: var(--mint-wash); }
.consent-row input { width: 20px; height: 20px; margin: 1px 0 0; accent-color: var(--mint-ink); cursor: pointer; }
.consent-row strong { display: block; font-size: 0.92rem; line-height: 1.35; }
.consent-row small { display: block; margin-top: 3px; color: var(--text-2); font-size: 0.82rem; line-height: 1.45; }

.drop-zone {
  width: 100%;
  margin-top: 10px;
  display: flex;
  align-items: center;
  gap: 12px;
  padding: 14px;
  border: 1.5px dashed var(--mint-ink);
  border-radius: var(--radius-sm);
  background: var(--paper);
  color: var(--text);
  text-align: left;
  cursor: pointer;
  transition: background-color 140ms ease, border-color 140ms ease;
}
.drop-zone svg { color: var(--mint-ink); }
.drop-zone:hover, .drop-zone.is-dragging { background: var(--mint-wash); border-style: solid; }
.drop-text { display: grid; gap: 1px; min-width: 0; }
.drop-title { font-weight: 650; font-size: 0.95rem; }
.drop-help { color: var(--muted); font-size: 0.8rem; }
.drop-lock { display: none; color: var(--muted); font: 500 0.72rem/1.4 var(--mono); }
.drop-zone.is-disabled { border-color: var(--line-strong); background: var(--soft); color: var(--muted); cursor: not-allowed; }
.drop-zone.is-disabled svg { color: var(--line-strong); }
.drop-zone.is-disabled:hover { background: var(--soft); border-style: dashed; }
.drop-zone.is-disabled .drop-help { display: none; }
.drop-zone.is-disabled .drop-lock { display: block; }

.action-row { margin-top: 10px; display: flex; flex-wrap: wrap; gap: 8px; align-items: stretch; }
.demo-button {
  flex: 1 1 auto;
  min-height: 42px;
  display: inline-flex;
  align-items: center;
  justify-content: space-between;
  gap: 10px;
  padding: 8px 12px;
  border: 1px solid var(--line-strong);
  border-radius: var(--radius-sm);
  background: var(--paper);
  text-align: left;
  cursor: pointer;
}
.demo-button:hover { border-color: var(--text-2); }
.demo-label { font-size: 0.9rem; font-weight: 600; }
.demo-flag {
  padding: 2px 7px;
  border-radius: 999px;
  background: var(--blue-wash);
  color: var(--blue-ink);
  font: 600 0.66rem/1.5 var(--mono);
  letter-spacing: 0.04em;
  text-transform: uppercase;
  white-space: nowrap;
}
#analysis-status { margin-top: 10px; }
.progress-line { height: 3px; margin-top: 8px; border-radius: 2px; background: var(--line); overflow: hidden; }
.progress-line span { display: block; width: 0; height: 100%; background: var(--mint-ink); transition: width 100ms linear; }

/* Disclosures */
.more { margin-top: 14px; border-top: 1px solid var(--line); }
.more:not([open]) > :not(summary) { display: none; }
.more > summary {
  min-height: 40px;
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 10px;
  padding: 10px 0 0;
  color: var(--text-2);
  font-size: 0.88rem;
  font-weight: 600;
  list-style: none;
  cursor: pointer;
}
.more > summary::-webkit-details-marker { display: none; }
.more > summary::after {
  content: "";
  width: 7px;
  height: 7px;
  margin-right: 4px;
  border-right: 1.6px solid currentColor;
  border-bottom: 1.6px solid currentColor;
  transform: translateY(-2px) rotate(45deg);
  transition: transform 140ms ease;
}
.more[open] > summary::after { transform: translateY(1px) rotate(-135deg); }
.more > summary:hover { color: var(--text); }
.more-body { display: grid; gap: 8px; padding-top: 8px; color: var(--text-2); font-size: 0.86rem; }
.more-body ul { display: grid; gap: 6px; padding-left: 18px; }
.more-body h4 { color: var(--text); font-size: 0.86rem; }
.details-body { display: grid; gap: 14px; padding-top: 12px; }
.details-body > .more-body,
.details-body > .evidence-ladder,
.details-body > .discussion-prompt { margin-top: 0; padding-top: 0; }
.topic-evidence .topic-sections { margin-top: 10px; }
.more-body .link-list { list-style: none; padding-left: 0; gap: 4px; }

/* Help */
.help {
  margin-top: 28px;
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 0 28px;
  align-items: start;
}
.help .more { margin-top: 0; }
.help .more > summary { min-height: 48px; padding: 0; }
.help .more[open] { padding-bottom: 14px; }
.glossary { display: grid; grid-template-columns: max-content minmax(0, 1fr); gap: 6px 14px; }
.glossary dt { font-weight: 650; color: var(--text); }

/* Results */
.results { margin-top: 20px; }
.results-card { display: grid; gap: 16px; }
.results-heading {
  display: grid;
  grid-template-columns: minmax(0, 1fr) auto;
  gap: 16px 24px;
  align-items: start;
}
.results-meta { display: flex; flex-wrap: wrap; align-items: center; gap: 8px; }
.results-heading h2 { margin-top: 4px; font-size: clamp(1.25rem, 1rem + 1vw, 1.6rem); line-height: 1.2; letter-spacing: -0.02em; }
.result-summary { margin-top: 4px; color: var(--muted); font-size: 0.88rem; }
.result-summary:empty { display: none; }
.synthetic-badge {
  padding: 2px 8px;
  border-radius: 999px;
  background: var(--blue-wash);
  color: var(--blue-ink);
  font: 600 0.66rem/1.5 var(--mono);
  letter-spacing: 0.05em;
}
.results-actions { display: flex; flex-wrap: wrap; gap: 8px; justify-content: flex-end; }

.status-banner {
  padding: 12px 16px;
  border: 1px solid var(--mint-line);
  border-left: 4px solid var(--mint-ink);
  border-radius: var(--radius-sm);
  background: var(--mint-wash);
}
.status-banner[data-state="abstain"] { border-color: var(--amber-line); border-left-color: var(--amber-ink); background: var(--amber-wash); }
.status-banner strong, .status-banner span { display: block; }
.status-banner strong { font-size: 1rem; line-height: 1.35; }
.status-banner span { margin-top: 2px; color: var(--text-2); font-size: 0.88rem; }
.status-banner span:empty { display: none; }

.panel {
  min-width: 0;
  padding: 18px;
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  background: var(--paper);
}
.panel h3 { font-size: 1rem; line-height: 1.3; }
.panel-head { display: flex; align-items: flex-start; justify-content: space-between; gap: 12px; }
.panel-head h3 { margin-top: 3px; font-size: 1.08rem; }
.finding-badge {
  flex-shrink: 0;
  padding: 3px 9px;
  border: 1px solid var(--amber-line);
  border-radius: 999px;
  background: var(--amber-wash);
  color: var(--amber-ink);
  font: 700 0.68rem/1.5 var(--mono);
  letter-spacing: 0.06em;
  white-space: nowrap;
}
.finding-badge[data-state="supported"] { border-color: var(--mint-line); background: var(--mint-wash); color: var(--mint-deep); }
.finding-badge:empty { display: none; }
.finding-lede { margin-top: 10px; font-size: 0.95rem; }
.finding-lede:empty { display: none; }

.evidence-ladder { list-style: none; margin-top: 12px; border-top: 1px solid var(--line); }
.evidence-step {
  display: grid;
  grid-template-columns: 28px minmax(130px, 0.3fr) minmax(0, 1fr) auto;
  gap: 4px 14px;
  align-items: baseline;
  padding: 9px 0;
  border-bottom: 1px solid var(--line);
}
.evidence-step > * { min-width: 0; }
.step-index { color: var(--mint-ink); font: 600 0.72rem/1 var(--mono); }
.evidence-step strong { font-size: 0.88rem; }
.evidence-step p { color: var(--muted); font-size: 0.84rem; overflow-wrap: anywhere; }
.step-state {
  justify-self: end;
  padding: 2px 8px;
  border-radius: 999px;
  background: var(--soft);
  color: var(--muted);
  font: 600 0.64rem/1.5 var(--mono);
  letter-spacing: 0.05em;
  text-transform: uppercase;
  white-space: nowrap;
}
.evidence-step[data-state="passed"] .step-state,
.evidence-step[data-state="observed"] .step-state { background: var(--mint-wash); color: var(--mint-deep); }
.evidence-step[data-state="stopped"] .step-state,
.evidence-step[data-state="unknown"] .step-state { background: var(--amber-wash); color: var(--amber-ink); }
.evidence-step[data-state="context only"] .step-state { background: var(--blue-wash); color: var(--blue-ink); }

.discussion-prompt { margin-top: 14px; padding: 12px 14px; border-radius: var(--radius-sm); background: var(--soft); }
.discussion-prompt p { margin-top: 4px; font-size: 0.9rem; }
.source-block { margin-top: 12px; display: flex; flex-wrap: wrap; align-items: center; gap: 6px 14px; }
.source-block .panel-label { color: var(--muted); }
.source-links { display: flex; flex-wrap: wrap; gap: 4px 14px; font-size: 0.86rem; }

.file-grid { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 16px; align-items: start; }
.metric-grid {
  margin-top: 12px;
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(min(100%, 120px), 1fr));
  gap: 1px;
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  background: var(--line);
  overflow: hidden;
}
.metric-grid:empty { display: none; }
.metric { min-width: 0; padding: 10px 12px; background: var(--paper); }
.metric span { display: block; color: var(--muted); font: 600 0.62rem/1.3 var(--mono); letter-spacing: 0.08em; text-transform: uppercase; }
.metric strong { display: block; margin-top: 4px; font-size: 0.95rem; line-height: 1.25; overflow-wrap: anywhere; }
.chart-heading { margin-top: 16px; font-size: 0.84rem; color: var(--muted); font-weight: 600; }
.chromosome-chart {
  width: 100%;
  max-width: 100%;
  min-height: 210px;
  margin-top: 6px;
  display: flex;
  align-items: flex-end;
  gap: clamp(2px, 0.4vw, 5px);
  border-bottom: 1px solid var(--line-strong);
  overflow-x: auto;
}
.chromosome-bar { flex: 1 0 10px; min-width: 10px; height: 200px; display: flex; flex-direction: column; justify-content: flex-end; align-items: center; gap: 4px; }
.chromosome-bar i {
  width: 100%;
  max-width: 18px;
  min-height: 4px;
  border-radius: 2px 2px 0 0;
  background: linear-gradient(180deg, var(--mint), var(--blue));
  transform-origin: bottom;
  animation: grow 520ms cubic-bezier(0.2, 0.8, 0.2, 1) both;
}
.chromosome-bar span { color: var(--muted); font: 500 0.58rem/1.2 var(--mono); }
.chart-note { margin-top: 8px; color: var(--muted); font-size: 0.78rem; }

.check-list { margin-top: 10px; border-top: 1px solid var(--line); }
.check-row {
  display: grid;
  grid-template-columns: 52px minmax(0, 1fr);
  gap: 0 10px;
  align-items: baseline;
  padding: 8px 0;
  border-bottom: 1px solid var(--line);
}
.check-row > * { min-width: 0; }
.check-state {
  justify-self: start;
  padding: 1px 6px;
  border-radius: 4px;
  background: var(--amber-wash);
  color: var(--amber-ink);
  font: 700 0.62rem/1.5 var(--mono);
  letter-spacing: 0.05em;
}
.check-state.pass { background: var(--mint-wash); color: var(--mint-deep); }
.check-row b { font-size: 0.86rem; font-weight: 600; }
.check-row small { grid-column: 2; color: var(--muted); font-size: 0.78rem; overflow-wrap: anywhere; }
.provenance-strip {
  margin-top: 12px;
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 1px;
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  background: var(--line);
  overflow: hidden;
}
.provenance-strip div { min-width: 0; padding: 8px 10px; background: var(--soft); }
.provenance-strip span { display: block; color: var(--muted); font: 600 0.6rem/1.3 var(--mono); letter-spacing: 0.08em; text-transform: uppercase; }
.provenance-strip strong { display: block; margin-top: 2px; font: 500 0.8rem/1.35 var(--mono); overflow-wrap: anywhere; }

.capability-grid { margin-top: 10px; display: grid; gap: 8px; }
.capability {
  min-width: 0;
  display: grid;
  grid-template-columns: 74px minmax(0, 1fr);
  gap: 2px 10px;
  align-items: baseline;
}
.capability-code {
  grid-row: span 2;
  justify-self: start;
  padding: 1px 6px;
  border: 1px solid var(--line-strong);
  border-radius: 4px;
  color: var(--muted);
  font: 600 0.62rem/1.5 var(--mono);
  letter-spacing: 0.05em;
  white-space: nowrap;
}
.capability[data-state="supported_observation"] .capability-code { border-color: var(--mint-line); color: var(--mint-deep); background: var(--mint-wash); }
.capability h4 { font-size: 0.88rem; }
.capability p { color: var(--muted); font-size: 0.8rem; }
.warnings-panel ul { margin-top: 10px; display: grid; gap: 6px; padding-left: 18px; color: var(--text-2); font-size: 0.84rem; }
.results-card > .more { margin-top: 0; }
.results-card > .more > summary { padding-top: 14px; }

/* Footer */
.site-footer { margin-top: 36px; padding: 18px 0; background: var(--navy); color: var(--on-navy-muted); font-size: 0.84rem; }
.footer-inner { display: flex; flex-wrap: wrap; align-items: center; justify-content: space-between; gap: 8px 20px; }
.footer-brand { display: inline-flex; align-items: center; gap: 8px; color: #fff; font-weight: 650; }
.footer-brand img { border-radius: 5px; }
.site-footer a { color: var(--mint); }

.toast {
  position: fixed;
  z-index: 50;
  left: 50%;
  bottom: 20px;
  transform: translateX(-50%);
  width: min(560px, calc(100% - 32px));
  padding: 12px 16px;
  border: 1px solid var(--red-line);
  border-left: 4px solid var(--red-ink);
  border-radius: var(--radius-sm);
  background: var(--paper);
  color: var(--text);
  font-size: 0.92rem;
  box-shadow: 0 18px 50px rgba(9, 17, 31, 0.22);
}

@keyframes grow { from { opacity: 0.25; transform: scaleY(0.05); } }

/* Responsive */
@media (max-width: 900px) {
  .workspace { grid-template-columns: minmax(0, 1fr); }
  .file-grid { grid-template-columns: minmax(0, 1fr); }
  .results-heading { grid-template-columns: minmax(0, 1fr); }
  .results-actions { justify-content: flex-start; }
}

@media (max-width: 640px) {
  :root { --gutter: 24px; }
  .hero { padding: 16px 0 64px; }
  .workspace { margin-top: -46px; gap: 14px; }
  .side { gap: 14px; }
  .card { padding: 16px; }
  .panel { padding: 14px; }
  .help { grid-template-columns: minmax(0, 1fr); margin-top: 20px; }
  .medicine-grid { grid-template-columns: repeat(auto-fill, minmax(min(100%, 140px), 1fr)); }
  .medicine-card { min-height: 58px; padding: 10px 12px; }
  .topic-sections { grid-template-columns: minmax(0, 1fr); gap: 2px; }
  .topic-sections dd + dt { margin-top: 8px; }
  .evidence-step { grid-template-columns: 24px minmax(0, 1fr); gap: 3px 10px; }
  .evidence-step p, .step-state { grid-column: 2; }
  .step-state { justify-self: start; }
  .results-actions .button { flex: 1 1 100%; }
  .glossary { grid-template-columns: minmax(0, 1fr); gap: 0; }
  .glossary dd { margin-bottom: 6px; }
}

@media (max-width: 420px) {
  :root { --gutter: 20px; }
  h1, h2, h3, h4, p, li, a, dt, dd, summary, strong, small, span, button, label { overflow-wrap: anywhere; }
  .finding-badge, .step-state, .count, .demo-flag { white-space: normal; }
  .panel-head { flex-direction: column; gap: 8px; }
  .chromosome-chart {
    min-height: 0;
    display: grid;
    grid-template-columns: repeat(6, minmax(0, 1fr));
    gap: 10px 5px;
    overflow: visible;
  }
  .chromosome-bar { min-width: 0; height: 92px; }
  .chromosome-bar i { max-width: 16px; max-height: 74px; }
  .capability { grid-template-columns: minmax(0, 1fr); }
  .capability-code { grid-row: auto; }
  .footer-inner { flex-direction: column; align-items: flex-start; }
}

@media (prefers-reduced-motion: reduce) {
  html { scroll-behavior: auto; }
  *, *::before, *::after {
    scroll-behavior: auto !important;
    animation-duration: 0.01ms !important;
    animation-iteration-count: 1 !important;
    transition-duration: 0.01ms !important;
  }
}

@media (forced-colors: active) {
  .medicine-card[aria-expanded="true"] { outline: 2px solid CanvasText; }
  .synthetic-badge, .finding-badge, .step-state, .check-state, .capability-code, .medicine-added, .demo-flag, .tag, .provenance { border: 1px solid CanvasText; }
  .question-item.is-editing { outline: 2px solid CanvasText; }
}

@media print {
  .site-header, .hero, .workspace, .help, .site-footer, .results-actions, .results .more > summary, .toast, .skip-link { display: none !important; }
  .results .more { border: 0; }
  .results .more > :not(summary) { display: grid !important; }
  body { color: #0d1a2b; background: #fff; }
  .wrap { width: auto; }
  .results { display: block !important; margin: 0; }
  .card, .panel, .metric, .provenance-strip div { color: #0d1a2b; background: #fff; border-color: #cad4d1; box-shadow: none; }
  .panel { break-inside: avoid; }
}
@media print {
  .results details::details-content { content-visibility: visible; display: contents; }
}